Physiology Viva Questions for Prof / Stage (1st Year MBBS)


Speaking metaphorically, Physiology is a Godzilla — not in terms of difficulty but in terms of size. And if someone, a brave soul decides to study Guyton and Hall’s Physiology, he’ll get his mind numb and would frequently experience study-burnouts without significant learning outcomes. Don’t go the hard way… instead you should choose the smart way. And you can do that by conceptual learning (meaning, the ability to explain something with utter simplicity) which is highly effective and is key to acing your Physiology Viva.

As, Alber Einstein said:

“If you cannot explain it simply, you don’t understand it well.”

And we would highly recommend that you use Guyton’s Physiology as a reference book and NOT as your main book. Because you would never be able to revise it during your exam preparation. It would be great if you use a combination of two books i.e Kaplan and Pocket Guyton. They work best together!

Studying from Guyton would make you feel like Jon Snow at the end… 😀

Yes, you’re Jon Snow… and you know NOTHING! 😀



Physiology Viva Questions for 1st Year MBBS

Below are the high-yield and frequently asked Physiology viva question in 1st Year MBBS prof / stage. They were submitted by the students of Bolan Medical College, Quetta.

Physiology Viva Internal Examiner (2017)

Dr. Alam Mengal

  1. What are Agglutinins?
  2. What would happen if I sever your adrenal gland? (PLOT TWIST: You do not die… now tell me!) 😀
  3. How much anticoagulant will be required/present in 5 liter of blood?
  4. what happens in RIGHT or LEFT bundle block?
  5. What are Korotkoff sound phases?
  6. What are alveolar cells?
  7. Surfactant’s composition, function, cells involved producing it and what happens if it’s deficient? How would you treat its deficiency?
  8. ECG Waves
  9. Blood pressure, pulse pressure and mean blood pressure
  10. Neuromuscular Junctions
  11. Sliding filament
  12. Sarcomere (deep) power stroke
  13. Antibodies and their types
  14. Life span of of various blood cells > Why do RBCs die after 120 days?
  15. Formation of Hemoglobin?
  16. Formation of RBCs and WBCs cells?
  17. Action potential (mechanism)
  18. Resting potential
  19. What is intrinsic factor? Its secretion and function inside body?
  20. What is Athele’s Heart? How one develops it?
  21. RBC Count in adult male, female and neonate?
  22. What is ESR? Its value in adult male, female and neonate?
  23. Significance of Reticulocyte count?
  24. Tell me, which of these would have fastest conduction velocity: Peripheral Nerve or
  25. Cutaneous Nerve
  26. What is Phanthom Limb?
  27. In which clinical condition we would observe “T-Wave Inversion”?
  28. What will you observe in ECG in case of Bundle Block?
  29. What are the different Heart Sounds?
  30. Tell me the differences between Atrial Flutter and Fibrilliation?
  31. Baroreceptor Reflex?
  32. In which type of muscle, both the Sodium/Potassium and Sodium/Calcium pumps are
  33. present?
  34. Haldane Effect?
  35. What is Action Potential and Resting Membrane Potential?
  36. What is Neuroglia?
  37. What is the prinicple of dialysis? Effect of kidney failure on heart?
  38. What is the difference between Myoglobin and Heamoglobin?
  39. How would you treat Erythroblastosis Foetalis?
  40. Types of Anemia? What is Spherocytosis? Polycythemia Vera?
  41. What is Pseudo Unipolar Neuron
  42. Tell me the types of nerve fibers and also of the Motor Nerve Types?
  43. What is Shock? Tell me its types?
  44. What is Preload and Afterload?
  45. Effect of Myocardial Infaraction on ECG?
  46. Define the Frank Starling Law?
  47. How would you measure ECF of a patient?
  48. Composition of Pus?
  49. What is Spirometry?
  50. What is Lung Function Test?
  51. What is Prothrombin Time?
  52. How would you prove that SA Node is the Pacemaker of the Heart?
  53. What will happen to a person if the S.A Node of his heart is is sever?
  54. How would you differntiate absolute refractory period from relative refractory period?
  55. Neurotransmitter and muscular endplate?
  56. Osponization?

Physiology Viva Internal Examiner (2014)

Prof: Dr. Abdul Rehman (H.O.D Physiology)
Topics: Respiration and Cardiovascular System

Unit: Respiration

  1. Pulmonary volumes
  2. Pulmonary capacities
  3. Respiratory center and its functions
  4. Role of centeral chemoreceptors in regulation of respiration
  5. Role of peripheral chemoreceptors in regulation of respiration
  6. J Receptors
  7. Dead space and its significance
  8. Respiratory unit
  9. Respiratory membranes
  10. Bohr’s effect
  11. Haldene’s effect
  12. Hering-Breurer’ Reflex
  13. Oxygen Hemoglobin Dissocaition Curve
  14. Transport of Carbon dioxide
  15. Formation of bicarbonate ion
  16. Intrapleural pressure
  17. Transpulmonary pressure
  18. Respiratory Minute Volume
  19. Respiratory Distress Syndrome
  20. Surfactant composition and function
  21. Lung compliance
  22. Ventilation Perfusion Ratio

UNIT: Cardiovascular System

  1. Cardiac cycle and its phases
  2. Cardiac output
  3. Stroke output
  4. Conductive system of heart
  5. Atrioventricular block (all 3 stages)
  6. Heart sounds and murmers
  7. Heart valves, their pattern of closeure and function
  8. Electrocardiogram (drawn on a paper, student will be asked different sagments and
  9. discuss relevant clinics)
  10. Why S.A Node is pacemaker of heart?
  11. Ectopic pacemaker

Physiology Viva External Examiner

Teacher name: Unknown 😀

  1. Extrinsic pathway of clotting
  2. Intrinsic pathway of clotting
  3. All clotting factors
  4. Types of Hemoglobin
  5. Formation of Hemoglobin
  6. Anemias amd its types including causes
  7. Policythemia and its types including causes
  8. Leukopenia
  9. Thrombicytopenia
  10. Purpora and its types and causes
  11. Hemostasis and its stages
  12. Anti-coagulants
  13. Erythroblastosis fetalis
  14. Blood cell counts and clinical reasons for its difference in males and females
  15. Platelete count
  16. W.B.C count
  17. Hemoglobin concentration in red blood cell and their oxygen carrying capacity
  18. Types of lymphocytes
  19. Types of T-lymphocytes
  20. Why B and T lymphocytes are named so?
  21. Achalasia
  22. Common bile duct opens into?
  23. Bile salts
  24. Pancreatic secretions
  25. Gastric secretions
  26. Harmones of G.I.T, their function and site of secretion
  27. Phases of deglutation (swallowing)
  28. Gastrocholic reflex



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