Causes of Anion Gap Metabolic Acidosis Mnemonic [MUDPILES + GOLDMARK]


Mastering Anion Gap Metabolic Acidosis Causes with a Simple Mnemonic Technique 

Greetings, medicos! 🙂 Today, in this article, we’re delving into an important topic in the realm of basic medical sciences: Anion Gap Metabolic Acidosis Causes. As you embark on this enlightening journey to become well-rounded medical students and competent physicians, understanding this condition is crucial. To aid you in your journey for knowledge, I’ve brought you two ingenious mnemonic techniques that will not only make memorizing the causes of Anion Gap Metabolic Acidosis crystal easy but also ensure they stick with you for many years to come.

In this engaging lesson, we’ll dissect the complexities of Anion Gap Metabolic Acidosis, breaking down the science behind it into easy-to-digest facts. So, let’s dive in and decipher this medical mystery together so that you are confident in your med-school exams and hospital ward rounds!

Causes of Anion Gap Metabolic Acidosis Mnemonic

One of the most common medical mnemonics to learn the anion gap metabolic acidosis causes is “MUDPILES”.

Courtesy: Osmosis.Org


Let’s break down the mnemonic for a moment of clarity:

  • M – Methanol
  • U – Uremia
  • D – Diabetic ketoacidosis
  • P – Propylene Glycol
  • I – Isoniazid
  • L – Lactic Acidosis
  • E – Ethylene Glycol
  • S – Salicylates


There is another innovative anion gap metabolic acidosis mnemonic, aptly named “GOLD MARK,” stems from a 2008 article in The Lancet.

Breaking down the updated mnemonic:

  • G – Glycols (ethylene glycol and propylene glycol)
  • O – Oxoproline
  • L – L-Lactate
  • D – D-Lactate
  • M – Methanol
  • A – Aspirin
  • R – Renal Failure
  • K – Ketoacidosis

We hope that you find this mnemonic useful in memorizing the causes of anion gap metabolic acidosis. Happy learning, folks! 🙂

Bonus: Equation to calculate the anion gap

Wondering how to calculate the anion gap using a formula?

Fear not as we got you covered here! 🙂

Here’s the simple equation/formula to calculate the anion gap:

Anion Gap = (Na+ + K+) – (Cl- + HCO3-)


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